Neurotrophins: A Ticket to Ride for BDNF

نویسندگان

  • Kerrie Thomas
  • Alun Davies
چکیده

The secretion of BDNF from neurons is under activity-dependent control: this is crucial for the formation of appropriate synaptic connections during development and for learning and memory in adults. New evidence shows that interaction between a motif in the tertiary structure of BDNF and the sorting receptor carboxypeptidase E directs this neurotrophin to the regulated secretory pathway.

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عنوان ژورنال:
  • Current Biology

دوره 15  شماره 

صفحات  -

تاریخ انتشار 2005